Predictable suppression of gene expression by 5′-UTR-based RNA quadruplexes
نویسندگان
چکیده
منابع مشابه
Predictable suppression of gene expression by 5′-UTR-based RNA quadruplexes
Four-stranded DNA and RNA quadruplexes or G4 motifs are non-B DNA conformations that are presumed to form in vivo, although only few explicit evidence has been reported. Using bioinformatics the presence of putative DNA G-quadruplexes within critical promoter regions has been demonstrated and a regulatory role in transcription has been suspected. However, in genomic DNA the presence of the comp...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2009
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkp696